Coding
Part:BBa_K3590018:Design
Designed by: Barbora Hrnčířová Group: iGEM20_Brno_Czech_Republic (2020-10-18)
Cohesin derived from Clostridium thermocellum
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
The sequence was codon-optimized for expression in Bacillus subtilis.
Source
The original sequence of CohCt was taken from the Scaf19L sequence published in the article by Vazana and colleagues (2013). The sequence was codon-optimized for expression in Bacillus subtilis.
Vazana Y., Barak Y., Unger T., Peleg Y., Shamshoum M., Ben-Yehezkel T., Mozor Y., Shapiro E., Lamed R. and Bayer E. A. 2013. A synthetic biology approach for evaluating the functional contribution of designer cellulosome components to deconstruction of cellulosic substrates. Biotechnol. Biofuels 6: 182. DOI: 10.1186/1754-6834-6-187